RNA Details
Disease Name
pulmonary fibrosis
Tissue
lung
RNA Symbol
SMAD3
RNA ID
RNA Type
mRNA
Alteration Pattern
dna hypomethylation
Species
homo sapiens
Detection Methods
PCR; ELISA; Mass spectrometry etc.
Target
NA
Pathway
NA
PubMed ID
Title
The correlation between pulmonary fibrosis and methylation of peripheral Smad3 in cases of pigeon breeder's lung in a Chinese Uygur population
Year
2017
Function
"Smad3 gene hypomethylation might promote pulmonary fibrosis in Uygur PBL patients via increased Smad3 mRNA expression. Smad3 methylation, Smad3 mRNA expression and TGF-B level were correlated with the number of pigeons bred by patients."